Donepezil, marketed under the trade name. Aricept, is a medication used in the palliative treatment of, alzheimer's disease. 1 2, donepezil is used to improve cognition and behavior of people with Alzheimer's, but does not slow the progression of or cure the disease. 3, common side effects include loss of appetite, gastrointestinal upset, diarrhea, action of aricept difficulty sleeping, vomiting, or muscle cramping. 4, it was developed by, eisai and. Pfizer and is sold as a generic by multiple suppliers. Donepezil action of aricept acts as a centrally acting reversible acetylcholinesterase inhibitor. 5, contents, medical uses edit, alzheimer's disease edit, there is no evidence that donepezil or other similar action of aricept agents alters the course or progression of, alzheimer's disease. 6 to 12-month controlled studies have shown modest benefits in cognition and/or behavior. 3, the UK, national Institute for Clinical Excellence (nice) recommends donepezil as an option in the management of mild to moderate Alzheimer's disease. 6, the person should, however, be reviewed frequently and if there is no significant benefit it should be stopped. 6, in 2006 the.S. Food and Drug Administration also approved donepezil for treatment of mild, moderate and severe dementia in Alzheimer's disease. 7, adverse effects edit. In action of aricept clinical trials the most common adverse events leading to discontinuation were nausea, diarrhea, and vomiting. 8 9 Other side effects included difficulty sleeping, muscle cramps and loss of appetite. Most side effects were observed in patients taking the 23 mg dose compared to 10 mg or lower doses. Side effects improved with continued use. 10 Precautions edit Donepezil should be used with caution in people with heart disease, cardiac conduction disturbances, chronic obstructive pulmonary disease, asthma, severe cardiac arrhythmias and sick sinus syndrome. 10 People with peptic ulcer disease or taking nsaids should use caution because increased risk of gastrointestinal bleeding was noted. 10 Slow heart beat and fainting in people with heart problems were also seen. These symptoms may appear more frequent when initiating treatment or increasing the donepezil dose. Although action of aricept occurrence of seizures is rare, people who have a predisposition to seizures should be treated with caution. 10 Mechanism of action edit Donepezil binds and reversibly inactivates the cholinesterases, thus inhibiting hydrolysis of acetylcholine. This increases acetylcholine concentrations at cholinergic synapses.

Eisai aricept

Donepezil, marketed under the trade name. Aricept, is a medication used in the palliative treatment of, alzheimer's disease. 1 2, donepezil is used to improve cognition and behavior of people with Alzheimer's, but does not slow the progression of or cure the disease. 3, common side effects include loss of appetite, gastrointestinal upset, diarrhea, difficulty sleeping, vomiting, or muscle cramping. 4, it was developed by, eisai and. Pfizer and is sold as a generic by multiple suppliers. Donepezil acts as a centrally acting reversible acetylcholinesterase inhibitor. 5, contents, medical uses edit, alzheimer's disease edit, there is no evidence that donepezil or other similar eisai aricept agents alters the course or progression of, alzheimer's disease. 6 to 12-month controlled studies have shown modest benefits in cognition and/or behavior. 3, the UK, national Institute for Clinical Excellence (nice) recommends donepezil as an option in the management of mild to moderate Alzheimer's disease. 6, the person should, however, be reviewed frequently and if there is no significant benefit it should be stopped. 6, in 2006 the.S. Food and Drug Administration also eisai aricept approved donepezil for treatment of mild, moderate and severe dementia in Alzheimer's disease. 7, adverse effects edit. In clinical trials the most common adverse events leading to discontinuation were nausea, diarrhea, and vomiting. 8 9 Other side effects included difficulty sleeping, muscle cramps and loss of appetite. Most side effects were observed in patients taking the 23 mg dose compared to 10 mg or lower doses. Side effects improved with continued use. 10 Precautions edit Donepezil should be used with caution in people with heart disease, cardiac conduction disturbances, chronic obstructive pulmonary disease, asthma, severe cardiac arrhythmias and sick sinus syndrome.

Aricept package insert

Generic Name: donepezil hydrochloride, dosage Form: tablet, film coated; tablet-orally-disintegrating, show On This Page. View All, show On This Page 1 indications AND usage, aricept is indicated for the treatment of dementia of the Alzheimers type. Efficacy has been demonstrated in patients with mild, moderate, and severe Alzheimers disease. 2 dosage AND administration.1 Dosing in Mild to Moderate Alzheimers Disease. The recommended starting dosage of Aricept is 5 mg administered once per day in the evening, just prior to retiring. The maximum recommended dosage of Aricept in patients with mild to moderate Alzheimers disease is 10 mg per day. A dose of 10 mg should not be administered until patients have been on a daily dose of 5 mg for 4 to 6 weeks. 2.2 Dosing in Moderate to Severe Alzheimers Disease. The maximum recommended dosage of Aricept in patients with moderate to severe Alzheimers disease is 23 mg per day. A dose of 23 mg per day should not be administered until patients have been on a daily dose of 10 mg for at least 3 months. 2.3 Administration Information, aricept should be taken in the evening, just prior to retiring. Aricept can be taken with or without food. The Aricept 23 mg tablet should not be split, crushed, or chewed. Allow Aricept ODT to dissolve on the tongue and follow with water. 3 dosage forms AND strengths. Aricept is supplied as film-coated, round tablets containing 5 mg, 10 mg, or 23 mg of donepezil hydrochloride. The 5 mg tablets are white. The strength, in mg (5 is debossed on one side and Aricept is debossed on the other side. The 10 mg tablets are yellow. The strength, in mg (10 is debossed on one side and Aricept is debossed on the other side.

Aricept

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